All PNCB certification programs have met the rigorous national accreditation standards of the National Commission for Certifying Agencies (NCCA). The NCCA is the designated Accreditation Council of the National Organization for Competency Assurance (NOCA).

Initially granted in 1996, PNCB accreditation is evaluated every five years. Following a thorough review of the information submitted by the PNCB in 2006, the Commission voted to renew the PNCB's accreditation through April 30, 2011.

PNCB certification programs are recognized by the National Council of State Boards of Nursing (NCSBN) and individual state boards of nursing. The PNCB is also a member of the American Board of Nursing Specialties (ABNS).